Top Shelf  Newfoundlands and Beagles

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Here at Top Shelf we test above and beyond the common health tests.. 

Below we have listed the tests we perform on our Beagle prior to breeding and the links to their explanations:

OFA Hips - offa.org

Another good link regarding hip dysplasia in Beagles

http://www.geocities.com/aladarbeagles/hd2.html

OFA Elbow - offa.org

OFA Cardiac - offa.org

CERF - eyes - http://www.vmdb.org/cerf.html

Factor VII deficiency - http://clubs.akc.org/NBC/factor7.html

MLS - Musladin-lueke syndrome - http://www.vgl.ucdavis.edu/services/MLS.php

PK - Pyruvate Kinase - http://clubs.akc.org/NBC/pyruvate_kinase.htm

Explanation of diseases that parents have been tested for

 Diseases that have DNA testing available to determine clear, carrier and affected dogs

 Factor VII Deficiency

 This disorder is known to cause a mild bleeding disorder in beagles. Only rare reports of severe bleeding have been reported. Most affected dogs actually remain totally asymptomatic. Affected dogs could exhibit an increased bleeding tendency following a trauma or surgery. The frequency of this problem is unknown but by testing we can avoid producing beagles that are affected with this deficiency.

 Pyruvate Kinase (PK) Deficiency

 This disorder is known to cause anemia in beagles.  A specific defect was discovered in the PK gene that causes the anemia. Affected beagles can be severely anemic and they generally die at a young age generally before 5 years of age. Symptoms vary but most are exercise intolerant and most have pale gums.  Many beagles with this disease will also have increased density of their bones. By testing all beagles before they are bred we can avoid producing beagles that are affected with this serious issue.

 Musladin-Lueke Syndrome (MLS)

 This is a genetic condition that affects the development and structure of connective tissue.  It tends to affect multiple organs, including bone, heart, skin, and muscle. The severity of clinical signs is variable. Some animals can live a fairly normal life with the disease. However others cannot be kept comfortable and may require euthanasia. Dogs that can function normally at maturity generally do not progress. This syndrome can be prevented by testing all beagles before they are bred.

 Diseases that parents are screened for but the exact genetic mechanism of inheritance has not been determined  

These diseases are ones that are felt to be genetic but the way that they are passed down to their offspring is unknown. By breeding clear parents the chances of getting an affected puppy are decreased but not completely eliminated. The things that fall into this category are testing for hip and elbow dysplasia, inherited heart defects, thyroid problems and different eye conditions. Most of the screenings need only be done one time although the eye exam (CERF) needs to be done on a yearly basis to keep the clearance current. Unfortunately some eye diseases may not show up until later in life so repeat certifications are required. 

 

Please ask your breeder or veterinarian if you have any questions on any of these diseases.

 

 

 

 

Check out Topshelf Newfoundlands on the OFA Website

 
click here

 

Newfoundland  Club of America click here

 

 

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Last Modified : 09/20/13 09:13 AM